As far as diabetes is concerned the early onset is scientifically named in the landmark study called TEDDY, or The Environmental Determination of Diabetes in the young
Principal TRIGRS are dairy and or wheat products given to a child at too young an age a ‘window of vulnerability” and auto immune reaction occurs
Wheat seed is modified by GMO to contain BT a bacillus with pesticidal properties courtesy of bio technology and dairy has rbgh hormones given to dairy producing cows to accelerate milk production
We need far more human clinical trials in the US to determine if these activties should be abolished as part of the Precautionary Principle to protect our children– a constitutional amendment making the precautionary principle a basic human right for our children
Here is speech given by Ed Rosenthal as Chair of the Walk to Cure Juvenile Diabetes in 2007 on the research to find a cure for Juvenile Diabetes.
Note the comments referencing Baby-DIAB and the TEDDY Study, The Environmental Determination of Diabetes in the young– dairy and wheat are trigrs.
I’m delighted to see here today so many friends and supporters of the Juvenile Diabetes Research Foundation Walk to Cure Diabetes.
The Foundation has set an ambitious goal for this year’s Walk–and with your help and dedication, I’m sure we’ll reach and even surpass our aspirations.
In this effort, money is essential.
However, this is about more than money. It’s about a precious asset…our children…and a priceless condition…their health.
As you know, diabetes exacts a terrible cost on our society–in terms of dollars…and in lost or diminished lives.
But obviously the human costs are even higher–in terms of lives snuffed out…or health reduced by diabetes-related heart attacks…strokes…kidney diseases…blindness or limb amputations.
But we’re not here to lament what diabetes does. We’re here to celebrate the fact that through JDRF, we can HELP PROVIDE THE RESOURCES TO CURE THIS TERRIBLE DISEASE.
I do hope you will leave here today with the same enthusiasm for JDRF and the March 18th Walk to Cure Diabetes. Other businesses, both large and small, have thrown their support to JDRF for two main reasons:
First, BECAUSE THE MONEY RAISED GOES TO THE BEST RESEARCHERS IN THE WORLD.
And second, because JDRF is extremely cost effective…in a typical year sending an incredible 85% to research.
That’s one of the reasons that Smart Money magazine placed JDRF in the top 10 “Charities You Can Trust”— you can be sure that your money is going where it’s promised!
Now I would like to add a few personal words about what I have learned about the disease known as Juvenile Diabetes
In all honesty, I was hesitant to agreeing to lead this campaign, since I also had no understanding of, what life was like with this disease and why it is so critical we give of ourselves to help fund the search for a cure.
So I am grateful to Daniel, a 9 year old child who spent part of his day, explaining to me what life was like since he was diagnosed with Juvenile Diabetes two years ago.
And although all kinds of diabetes are serious, his type, type 1 is more serious and is for life unless a cure is found.
Have you ever sat with a 9 year old child who as a matter of fact tells you : “Life was a…. whole lot…. easier before, but life is… not so easy now”
Imagine — -a nine year old commenting on how easy life was !!!!
Daniel described how he used to do chores, but his new chore is staying alive, counting carbs, testing blood sugar, taking shots 3 to 5 times per day everyday, just to stay alive. Daniel told me “Life is like a math problem.” He said “ if my blood sugar goes over 200, my body gets damaged a little bit”
He told me how, when he is invited to a birthday party, he needs to plan to give himself a “ tiny little bit more” insulin so he can negotiate having a piece of birthday cake.
Daniel is a type one (1) diabetic which, as he explained, is for life, and is a result of his pancreas having stopped the normal production of insulin.
Insulin shots are not a cure for Daniel,only life support. Type 1 diabetes is fatal 100% of the time. If Daniel stops taking insulin, he will die within a week or two…guaranteed, no exception. Daniel’s hope, his dream as he expressed it in his own words is: — “I very much look forward to the future when I can say: Mom, I have Juvenile Diabetes, lets go pick up the cure” Daniels 11 year old brother has other concerns which he expressed to his Mom:
“ Mom, if Daniel dies on the school bus coming home, am I going to be responsible ? ”…. We have to find a cure to this auto immune disease which kills off the cells needed for normal pancreatic function.
And the cure is close at hand. I have read some of the research, and I had the opportunity to interview Dr Aaron Kowalski, a member of a JDRF research team.
Dr Kowalski, himself and his brother, are both Type 1 diabetes.
He recounted the tremendous strides made over the past 30 years or so. In the 1970’s when his brother was 3 years old, his brother was diagnosed with Type 1 diabetes.
At that time that was a terrible diagnosis with certain diabetic complications which would lead to blindness, kidney disease, amputation and severely curtailed life expectancy. Today 28 years later both Dr Kowalski and his brother are hard at work trying to find a cure for the disease, so the obvious strides are apparent — they are both still here and contributing.
Diabetes is an auto-immune disease where the immune type T cells in the body get confused somehow and target the insulin producing cells wiping them out.
Type 1 diabetes people are particularly at risk because of the possibility of hypo-glycemia, a condition where blood sugar drops so low that the person may become unconscious or has seizures. This is obviously dangerous when driving a motor vehicle, but is particularly dangerous while sleeping, because often the individual does not know quick enough when the blood sugar has fallen to critical levels until it is too late. Once unconscious the condition is often fatal.
So what about the cure. The advent of stem cell research and the discovery of beta cells that can return the bodies cellular functions to normal, are accelerating the time frame when the cure will realistically be found. The state of the art procedure is called an IsLET Transplant where beta cells harvested from donor bodies are transplanted into type 1 patients. The landmark breakthrough result : People receiving Islet transplants do give up insulin.
Dr Kowalski calls an Islet Transplant “a life altering event,” returning the insulin producing beta cells back to the body which allows the insulin injections to stop.
So why doesn’t everybody get an Islet transplant?
As Dr Kowalski explained, as with all transplants, high powered drugs know as immuno -suppressants are used to stop the body from rejecting the transplant.
The problem with that, is the immuno -suppressants are inappropriate for children because the long term use of immuno suppressants can create a myriad of other health problems in the child due to the long term use.So the current research is trying to perfect the Islet Transplant where immuno-suppressants would be less pervasive. This research is focused on specifically targeting the insulin producing cells by developing targeted immune – suppressants. Additionally there is considerable research into the finding the cause, the TRIGR for Type 1 diabetes.
There is consensus that there is a genetic component involved, and that there are people more at risk than others. But the TRIGR, the insult to the body that triggers the onset of the disease remains unknown. TRIGR may be dietary or it may be environmental or a combination of factors, but this is where research needs to be focused. Reduced exposure to environmental toxins, prevention and diet, as well as other lifestyle changes may be the ultimate cure.
THE TEDDY STUDY
The Environmental Determination of Diabetes in the Young, acronym TEDDY, is designed to follow infants from birth thru adolescence, who are at genetic risk for type 1 diabetes. TEDDY’S primary aim is to identify infectious agents, dietary factors, or other environmental influences such as pesticides, that may increase the risk of developing type 1 diabetes. Researchers hope that this information will help them identify the influences leading to disease onset, how quickly the disease progresses and any protective factors which can be used.
The longer term goal is to find better ways of PREVENTING the disease, or at least slowing down or even potentially reversing its course
Investigators at six research sites in the United States and Europe, will screen over 200,000 infants from the general new born populations.
Infants who possess one or more of the gene combination putting them at high risk for developing type 1 diabetes, will be selected for closer study.
Seven thousand plus newborns will make up the study design. These seven thousand plus children will have blood samples drawn and tested every three months up to four years of age and then every six months up to fifteen years of age. The blood will be tested for auto-antibodies, markers of inflammation, as well as antibodies to viruses and other infectious agents ,vitamins, potential toxins and other environmental exposures. Stool samples, toenail clippings, and home tap water will also be collected and analyzed.
Previous studies such as BABY-DIAB based in Germany, found that infant diet may be associated with the risk of developing type 1 diabetes. Dr. Anette Zieglar, the BABY-DIAB principle investigator at the Institute for Diabetes in Munich, concludes
“We discovered that apart from genetic factors, infant diet maybe associated with the risk of developing type 1 diabetes, particularly the introduction of gluten-containing food or cereal too early in life”
A similar study in Colorado called DAISY, suggests that cereal introduction at too early an age raises the risk of autoantibody development
In the TEDDY study, investigators will look at family dynamics, stress, the presence of pets, as well as PESTICIDE EXPOSURE, vaccination history, and the introduction of certain foods such as infant formula, cow’s milk, cereals and other wheat products.
Researchers will also assess the infants weight and any history of viral infections such as mumps and others
Researchers hope that this long term study will provide the information to help them identify the influences leading to disease onset, how quickly the disease progresses, and any protective factors.
TEDDY may provide evidence that reduced exposure to environmental toxins such as pesticides as well as prevention and diet, and other lifestyle changes may be the ultimate cure.
What we can do is help, and that help is fund raising to continue the critical research. By becoming corporate sponsors of the Walk to Cure Juvenile Diabetes we can help.
The beneficiary will be children like Daniel and so many others.
And maybe, just maybe, we can make Daniel’s hope, his dream, a reality, so that one day soon when Daniel says :
“Mom let go pick up the cure”… she can say…. “Hop in the car and lets go get it!”
Thank you for supporting this worthwhile cause and the walk to find a cure.