By Sayer J. GreenMedInfo.com http://www.greenmedinfo.com/blog/alert-gmo-corn-and-roundup-caused-cancer-and-killed-rats
With Breast Cancer Awareness Month (BCAM) less than two weeks away, the latest bombshell GMO/Roundup study produced by a French research team, and presently making international headlines, is well-timed. The researchers found, in the first long-term GM corn and Roundup feeding study of its kind, that female rats, exposed to concentrations well below official safety limits, developed massive, progressive mammary tumors which either lead to premature death, or required euthanasia due to their great suffering.
In an alarming new study published in the journal Food and Chemical Toxicology, researchers from The Committee for Research & Independent Information on Genetic Engineering (CRIIGEN) reported on the results of a 2 year feeding study in rats given either NK603 Roundup-tolerant genetically modified maize, cultivated with or without Roundup, and Roundup alone, at levels permitted in drinking water and GM crops in the United States.
The authors of the study pointed out that currently, no regulatory authority requires mandatory chronic animal feeding studies to be performed for edible GMOs and formulated pesticides, and the only 90 day feeding trials were conducted by the biotech industry.
This study, therefore, was performed in light of this need, and the results were an unprecedented confirmation of the cancer-causing effects of GM food and agrichemicals, reported as follows:
In females, all treated groups died 2–3 times more than controls, and more rapidly. This difference was visible in 3 male groups fed GMOs. All results were hormone and sex dependent, and the pathological profiles were comparable. Females developed large mammary tumors almost always more often than and before controls, the pituitary was the second most disabled organ; the sex hormonal balance was modified by GMO and Roundup treatments. In treated males, liver congestions and necrosis were 2.5–5.5 times higher. This pathology was confirmed by optic and transmission electron microscopy. Marked and severe kidney nephropathies were also generally 1.3–2.3 greater. Males presented 4 times more large palpable tumors than controls which occurred up to 600 days earlier. Biochemistry data confirmed very significant kidney chronic deficiencies; for all treatments and both sexes, 76% of the altered parameters were kidney related. These results can be explained by the non linear endocrine-disrupting effects of Roundup, but also by the overexpression of the transgene in the GMO and its metabolic consequences. [emphasis added]
The conflict of interest here is as devastating as it is obvious, which is why we hope the new finding linking GM corn and Roundup herbicide to breast cancer will compel BCAM to respond, and change their awareness strategy to become more patient- versus industry-friendly. One thing is for sure. The study’s findings were not vague or equivocal, but disturbingly clear…
In an interview, Dr. Michael Antoniou, molecular biologist at Kings College, London, and a member of the CRIIGEN scientific council who funded the study, said
This is the most thorough research ever published into the health effects of GM food crops and the herbicide Roundup on rats. It shows an extraordinary number of tumors developing earlier and more aggressively – particularly in female animals. I am shocked by the extreme negative health impacts.
The rat has long been used as a surrogate for human toxicity. All new pharmaceutical, agricultural and household substances are, prior to their approval, tested on rats. This is as good an indicator as we can expect that the consumption of GM maize and the herbicide Roundup, impacts seriously on human health.
Here are some passages excerpted directly from the study
Suffering inducing euthanasia and deaths corresponded mostly in females to the development of large mammary tumors. These appeared to be clearly related to the various treatments when compared to the control groups. These tumors are generally known to be mostly estrogen-dependent (Harvell et al., 2000). We observed a strikingly marked induction of mammary tumors by R[roundup] alone, a major formulated pesticide, even at the very lowest dose administered. R[oundup] has been shown to disrupt aromatase which synthesizes estrogens (Richard et al., 2005)… [pg. 9]
In conclusion, it was previously known that glyphosate consumption in water above authorized limits may provoke hepatic and kidney failures (EPA). The results of the study presented here clearly demonstrate that lower levels of complete agricultural glyphosate herbicide formulations, at concentrations well below officially set safety limits, induce severe hormone-dependent mammary, hepatic and kidney disturbances. [pg. 10]