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Archive for June, 2014

Neurodevelopmental Disorders and Prenatal Residential Proximity to Agricultural Pesticides: The CHARGE Study http://ehp.niehs.nih.gov/1307044/

Gestational exposure to several common agricultural pesticides can induce developmental neurotoxicity in humans, and has been associated with developmental delay and autism. (more…)

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An acute exposure to glyphosate-based herbicide alters aromatase levels in testis and sperm nuclear quality. Round Up Herbicide results  in a rise of abnormal sperm morphology and a decrease of the expression of protamine 1 and histone 1 testicular in epididymal sperm are observed despite a normal sperm concentration and motility.

Highlights

We investigated the effects of a glyphosate-based herbicide after an 8-day exposure of adult rats.
We have shown a significant and differential expression of aromatase in testis.
We have observed a diminution of mRNA expression of nuclear markers in spermatozoa.
These results suggest changes in androgen/estrogen balance and in sperm nuclear quality. (more…)

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