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Archive for June, 2019

Cyanobacterial neurotoxin BMAA and brain pathology in stranded dolphins
David A. Davis, Kiyo Mondo, Erica Stern,Ama K. Annor, Susan J. Murch, Thomas M. Coyne, Deborah C. Mash Published: March 20, 2019

https://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0213346#sec017

Dolphin stranding events occur frequently in Florida and Massachusetts. Dolphins are an excellent sentinel species for toxin exposures in the marine environment. In this report we examine whether cyanobacterial neurotoxin, β-methylamino-L-alanine (BMAA), is present in stranded dolphins. BMAA has been shown to bioaccumulate in the marine food web, including in the muscles and fins of sharks. Dietary exposure to BMAA is associated with the occurrence of neurofibrillary tangles and β-amyloid plaques in nonhuman primates. The findings of protein-bound BMAA in brain tissues from patients with Alzheimer’s disease has advanced the hypothesis that BMAA may be linked to dementia. (more…)

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