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Archive for the ‘Auto Immune Disorders- Juvenile Diabetes’ Category

A two-phase study evaluating the relationship between Thimerosal-containing vaccine administration and the risk for an autism spectrum disorder diagnosis in the United States ” the present study provides new epidemiological evidence supporting an association between increasing organic-Hg exposure from Thimerosal-containing childhood vaccines and the subsequent risk of an ASD diagnosis.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878266/
David A Geier, Brian S Hooker,  Janet K Kern, Paul G King, Lisa K Sykes, and Mark R Geier

Results In phase I, it was observed that there was a significantly increased risk ratio for the incidence of ASD reported following the Thimerosal-containing DTaP vaccine in comparison to the Thimerosal-free DTaP vaccine. In phase II, it was observed that cases diagnosed with an ASD were significantly more likely than controls to receive increased organic-Hg from Thimerosal-containing hepatitis B vaccine administered within the first, second, and sixth month of life.

Conclusions: Routine childhood vaccination is an important public health tool to reduce the morbidity and mortality associated with infectious diseases, but the present study provides new epidemiological evidence supporting an association between increasing organic-Hg exposure from Thimerosal-containing childhood vaccines and the subsequent risk of an ASD diagnosis.

Autism spectrum disorder (ASD) is defined by standardized criteria of qualitative impairments in social interaction, qualitative impairments in communication, and restricted and stereotyped patterns of behavior, interests, and activities. A significant number of children diagnosed with ASD suffer a loss of previously-acquired skills, which is suggestive of neurodegeneration or a type of progressive encephalopathy with an etiological pathogenic basis occurring after birth. To date, the etiology of ASD remains under debate, however, many studies suggest toxicity, especially from mercury (Hg), in individuals diagnosed with an ASD. The present study evaluated concerns about the toxic effects of organic-Hg exposure from Thimerosal (49.55% Hg by weight) in childhood vaccines by conducting a two-phased (hypothesis generating/hypothesis testing) study with documented exposure to varying levels of Thimerosal from vaccinations. (more…)

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Recurrent 6th nerve palsy in a child following different live attenuated vaccines: case report
Daryl R Cheng, Nigel W CrawfordEmail author, Michael Hayman, Christopher Buckley and Jim P Buttery
BMC Infectious Diseases http://bmcinfectdis.biomedcentral.com/articles/10.1186/1471-2334-12-105

Abstract Background
Recurrent benign 6th nerve palsy in the paediatric age group is uncommon, but has been described following viral and bacterial infections. It has also been temporally associated with immunization, but has not been previously described following two different live attenuated vaccines. There is limited information in the literature regarding the safety of a repeat dose of a live vaccine in this setting. Future immunizations should be considered on a case-by-case basis.

Case presentation
A case is presented of a 12 month old Caucasian boy with recurrent benign 6th nerve palsy following measles-mumps-rubella and varicella vaccines, given on separate occasions with complete recovery following each episode. No alternate underlying etiology was identified despite extensive investigations and review.

Conclusions
The majority of benign 6th nerve palsies do not have a sinister cause and have an excellent prognosis, with recovery expected in most cases. The exact pathophysiology is unknown, although hypotheses including autoimmune mechanisms and direct viral invasion could explain the pathophysiology behind immunization related nerve palsies. It is important to rule out other aetiologies with thorough history, physical examination and investigations. There is limited information in the literature regarding the safety of a repeat dose of a live vaccine in this setting. Future immunizations should be considered on a case-by-case basis. (more…)

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The antibody aducanumab reduces Aβ plaques in Alzheimer’s disease

http://www.nature.com/nature/journal/v537/n7618/full/nature19323.html

Alzheimer’s disease (AD) is characterized by deposition of amyloid-β (Aβ) plaques and neurofibrillary tangles in the brain, accompanied by synaptic dysfunction and neurodegeneration. Antibody-based immunotherapy against Aβ to trigger its clearance or mitigate its neurotoxicity has so far been unsuccessful. Here we report the generation of aducanumab, a human monoclonal antibody that selectively targets aggregated Aβ. In a transgenic mouse model of AD, aducanumab is shown to enter the brain, bind parenchymal Aβ, and reduce soluble and insoluble Aβ in a dose-dependent manner. In patients with prodromal or mild AD, one year of monthly intravenous infusions of aducanumab reduces brain Aβ in a dose- and time-dependent manner. This is accompanied by a slowing of clinical decline measured by Clinical Dementia Rating—Sum of Boxes and Mini Mental State Examination scores. The main safety and tolerability findings are amyloid-related imaging abnormalities. These results justify further development of aducanumab for the treatment of AD. Should the slowing of clinical decline be confirmed in ongoing phase 3 clinical trials, it would provide compelling support for the amyloid hypothesis.

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Stay calm amid Zika–Zika is very mild (not unlike a cold) unless you have a compromised immune system. Then, if you do have compromised immunity and are Pregnant– be wary of spraying of Neurotoxin, Organophosphate-Naled, Larvicides and/or GMO Mosquitoes and Glyphosate.

The Zika virus was discovered in the year 1947 by the Rockefeller Foundation when it was isolated from monkeys from the Zika forest in Uganda in a laboratory. Since then the Foundation owns the patent to this virus. The first human case being detected in the year 1954 was found to cause a very mild form of disease involving low fever, sore body, headaches, and a mild rash in very few people. The rest did not show any symptoms at all. The symptoms were resolved in a few days

Doctors and researchers say the widespread use of the toxic chemicals heavily promoted by the chemical and pharmaceutical industry to combat mosquitoes is not preventing the spread of Zika virus, but is putting at risk the health of the general population. 

Experts in the field of genetics observed something very curious. The Zika virus had currently emerge exactly from those areas where the GM mosquitoes were released in 2015 to contain the dengue! The mosquitoes were released by a company called Oxitech in collaboration with the Bill & Melinda Gates Foundation (BMGF). Could one virus have been replaced with another?

http://www.greenmedinfo.com/blog/microcephaly-pesticides-once-again-crosshairs

GMWatch Reporter  http://www.greenmedinfo.com/gmi-blogs/gmwatch

http://www.greenmedinfo.com/blog/what-zika-virus-epidemic-covering

(more…)

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At Community Day School in Sarasota, Florida the Precautionary Principle was adopted by the schools board of directors. As a result no chemical pesticides are used in the school’s Papa Ed and Mimi Sustainable Garden or on the campus. Advocating the Precautionary Principle means to hold the pesticide accountable and  no pesticide or any chemical can be used around children unless the pesticide is PROVEN safe first not relatively safe but completely harmless.

The Precautionary Principle and the Community Day School adopting of APP flies in the face of the chemical pesticide industry which is protected by the pseudo science of ” relative toxicity” in which chemical pesticides are registered for use by and on its” relative safety.” This is pseudo science since the pesticides relative safety is determined by regulatory on its LD 50.

So what is an LD 50 that determines a pesticides relative safety ? An LD50  is the amount of the pesticide (the Lethal Dose) that kills 50% of the lab animals tested. Therefore according to the tenets of relative toxicity (or safety) the pesticide with the lowest amount of chemical that kills the 50 % of lab animals ( LD50 Lethal Dose) the relative toxicity is greater than a chemical which kills the 50% of lab animals with a lesser amount.Therefore the chemical which uses a greater amount that kills the same 50% of lab animals is RELATIVE SAFER. What a crock!  Now if you do not pause and consider that bizarre enough remember the testing is only on the 50% killed by the lethal dose, but what about the surviving 50% what conditions did those animals suffer. There is no data no testing no reporting required on the 50% of surviving animals. And that is all we have as a nation to protect our children from damage due to pesticides exposure.

Comments Sarah Catherine Leithauser-French on pesticide registration and the LD 50 registration ” With all the false labelling hiding GMOS in food & drink under natural sounding words. Surely not a funny jokes to the millions with GI issues, allergies, nervous system, neurological & other maladies already. Unconscionable. Opposite of the Golden Rule. Plus arrogantly, and without apology.What about their own children, relatives, grandchildren, or friends? I can’t understand it at all.”

Four in five U.S. children are exposed to organophosphate pesticides, mostly from food. (Though several studies have also linked organophosphate exposure in pregnant women and children to residential insecticide use in urban areas, where indoor pest control is common.) In addition to pesticides, almost all children also carry levels of lead, mercury, the plastics additive bisphenol A, flame retardants, and dozens of other untested chemicals in their bodies. (more…)

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How Society Subsidizes Big Food and Poor Health

http://archinte.jamanetwork.com/article.aspx?articleid=2530898

Approximately 80% of calories eaten in the United States are grown domestically.1 Yet, the US diet is a leading cause of morbidity. The analysis by Siegel et al2 in this issue of JAMA Internal Medicine suggests that through commodity subsidies that encourage poor diet we are, in part, paying for our own demise.

However, commodity subsidies are a small part of a bigger problem. From 2014 to 2023, the 2014 US Farm Bill will cost $956 billion (letter from D. W. Elmendorf to Frank D. Lucas, chair of the House Committee on Agriculture; http://www.cbo.gov/sites/default/files/cbofiles/attachments/hr2642LucasLtr.pdf), of which direct support for commodity production is only $44.5 billion over 10 years. Furthermore, among a range of agricultural products, farmers receive the greatest share of the retail price in beef and milk at 50% compared with only 7% for processed food, such as bread. So, while processed food prices may be low, commodity subsidies are not the primary cause.

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Association of Higher Consumption of Foods Derived From Subsidized Commodities With Adverse Cardiometabolic Risk Among US Adults

http://archinte.jamanetwork.com/article.aspx?articleid=2530901

Food subsidies are designed to enhance food availability, but whether they promote cardiometabolic health is unclear. Objective  investigate whether higher consumption of foods derived from subsidized food commodities is associated with adverse cardiometabolic risk among US adults.

Design, Setting, and Participants Cross-sectional analysis of the National Health and Nutrition Examination Survey data from 2001 to 2006. Our final analysis was performed in January 2016. Participants were 10 308 nonpregnant adults 18 to 64 years old in the general community.

Exposure From a single day of 24-hour dietary recall in the National Health and Nutrition Examination Survey, we calculated an individual-level subsidy score that estimated an individual’s consumption of subsidized food commodities as a percentage of total caloric intake.

Main Outcomes and Measures The main outcomes were body mass index (calculated as weight in kilograms divided by height in meters squared), abdominal adiposity, C-reactive protein level, blood pressure, non–high-density lipoprotein cholesterol level, and glycemia.

Conclusions and Relevance Among US adults, higher consumption of calories from subsidized food commodities was associated with a greater probability of some cardiometabolic risks. Better alignment of agricultural and nutritional policies may potentially improve population health.

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