In 2015 the World Health Organization’s International Agency for Research on Cancer (IARC) declared that glyphosate is “probably carcinogenic to humans”. Claims that glyphosate herbicides (which contain mixtures of chemicals) do not cause cancer are based on government regulators’ interpretations of industry’s own, commercially confidential, studies on glyphosate alone. In contrast, studies on Roundup and glyphosate published by independent scientists suggest that they cause cancer in laboratory animals. An in vitro study (not performed in living animals or humans) found that glyphosate disrupts hormones and made breast cancer cells proliferate at a level far below that permitted in drinking water in the EU. Controlled laboratory studies in rats are widely considered to be a good indicator of possible human cancer-causing effects of a chemical.

Studies in human populations have found an association between Roundup exposure and two types of blood cancer: An epidemiological study of pesticide applicators in the USA found that exposure to glyphosate herbicide was associated with higher incidence of multiple myeloma



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Cut Flowers—A Major Yet Little-Known Source of Toxic Pesticides Flower growers are actually among the heaviest users of agricultural chemicals, including pesticides that are suspected of being among the most toxic. This issue is not new.  The prevalence rates for abortion, prematurity, stillbirths, and malformations were estimated for pregnancies occurring among the female workers and the wives of the male workers before and after they started working in floriculture, and these rates were related to various degrees of exposure. A moderate increase in the prevalence of abortion, prematurity, and congenital malformations was detected for pregnancies occurring after the start of work in floriculture.” 

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Major Pesticides Are More Toxic to Human Cells Than Their Declared Active Principles


by Robin Mesnage,Nicolas Defarge, Joël Spiroux de Vendômois,  and Gilles-Eric Séralini

Pesticides are used throughout the world as mixtures called formulations. They contain adjuvants, which are often kept confidential and are called inerts by the manufacturing companies, plus a declared active principle, which is usually tested alone. We tested the toxicity of 9 pesticides, comparing active principles and their formulations, on three human cell lines (HepG2, HEK293, and JEG3). Glyphosate, isoproturon, fluroxypyr, pirimicarb, imidacloprid, acetamiprid, tebuconazole, epoxiconazole, and prochloraz constitute, respectively, the active principles of 3 major herbicides, 3 insecticides, and 3 fungicides. We measured mitochondrial activities, membrane degradations, and caspases 3/7 activities. Fungicides were the most toxic from concentrations 300–600 times lower than agricultural dilutions, followed by herbicides and then insecticides, with very similar profiles in all cell types. Despite its relatively benign reputation, Roundup was among the most toxic herbicides and insecticides tested. Most importantly, 8 formulations out of 9 were up to one thousand times more toxic than their active principles. Our results challenge the relevance of the acceptable daily intake for pesticides because this norm is calculated from the toxicity of the active principle alone. Chronic tests on pesticides may not reflect relevant environmental exposures if only one ingredient of these mixtures is tested alone. Continue Reading »

New Alzheimer’s treatment fully restores memory function
Of the mice that received the treatment, 75 percent got their memory functions back.
Australian researchers have come up with a non-invasive ultrasound technology that clears the brain of neurotoxic amyloid plaques – structures that are responsible for memory loss and a decline in cognitive function in Alzheimer’s patients.

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Stimulation of nicotinamide adenine dinucleotide biosynthetic pathways delays axonal degeneration after axotomy. Sasaki Y1, Araki T, Milbrandt J.

Abstract- Axonal degeneration occurs in many neurodegenerative diseases and after traumatic injury and is a self-destructive program independent from programmed cell death. Previous studies demonstrated that overexpression of nicotinamide mononucleotide adenylyltransferase 1 (Nmnat1) or exogenous application of nicotinamide adenine dinucleotide (NAD) can protect axons of cultured dorsal root ganglion (DRG) neurons from degeneration caused by mechanical or neurotoxic injury. Continue Reading »

Brain CT signs and the effect of alteplase after stroke 

The third International Stroke Trial (IST-3) is the largest (n=3035) randomised controlled trial of intravenous alteplase for acute ischaemic stroke to date. A meta-analysis of individual patient data from nine randomised trials (including IST-3) showed that intravenous alteplase improved outcome when administered up to 4·5 h after stroke onset.  The proportional benefit from alteplase increased with earlier treatment but was not modified by age.  IST-3 is a landmark study because the effects of alteplase could be assessed reliably in older patients with acute ischaemic stroke.

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Researchers warn that benzene, toluene, ethylbenzene and xylene may disrupt people’s hormone systems at levels deemed “safe” by feds  Published April 15, 2015 By Brian Bienkowski Environmental Health News ( see link below to complete article) http://www.environmentalhealthnews.org/ehs/news/2015/apr/endocrine-disruption-hormones-benzene-solvents

Four chemicals present both inside and outside homes might disrupt our endocrine systems at levels considered safe by the U.S. Environmental Protection Agency, according to an analysis released today.

The chemicals – benzene, toluene, ethylbenzene and xylene – are ubiquitous: in the air outside and in many products inside homes and businesses. They have been linked to reproductive, respiratory and heart problems, as well as smaller babies. Now researchers from The Endocrine Disruption Exchange (TEDX) and the University of Colorado, Boulder, say that such health impacts may be due to the chemicals’ ability to interfere with people’s hormones at low exposure levels. Continue Reading »


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